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Charlie Sheen's revelation of his HIV infection on Tuesday at the Today show stirred a barrage of comments from female friends and exes associated with the actor. Most of them frustrated why the actor is being silent about his condition all these years.

Jenny McCarthy, Sheen's co-star and close friend in Two And A Half Men, commented that the actor should have disclosed about the matter earlier.

"If I have to be upfront about a herpe how could you not be upfront about HIV? Being on Two and a Half Men myself and being on the show and playing a love interest you would think there would be some type of-I don't want to say-criminal issue but I don't even know how to feel about that. That could've been some valuable information," she said as mentioned in E! Online.

The SiriusXM radio show host's comment had since met questioning on Twitter with some pointing out that she is discriminating and asserting 'double standard' towards the actor.

In a lengthy statement, she clarified saying, "I am very aware that HIV is not spread through kissing, but I also believe that if an actress has to disclose all of her business before kissing a male costar, the actor should be required to disclose something as major as an HIV infection too. His disclosures in his personal life are none of my business, and are for him to reconcile with the people he interacted with privately. I am not one of them."

In another report from TMZ, adult star Elizabeth Bentley, meanwhile, said that she did not freak out when she knew about the actor's HIV confession.

The pornstar further said that during their previous sex acts, the actor has been very thoughtful to wear a condom every time thus she is positive that she did not get the disease from him

As for Sheen's ex-wife, Denise Hoffman, the actress is still keeping her silence and refused to comment about the actor's condition.

However, a source told People that the 44-year old actress already knew about the disease for 'a number of years.' Luckily, she and her two daughters, Lola and Sam have come out negative from their previous HIV tests.