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During this time of year, when it seems like everyone is sick with something, over-the-counter cold and flu remedies are flying off the shelves. Indeed, despite the fact that both the cold and flu are caused by viruses and thus need to simply run their course in the body, 70 percent of Americans turn to the pharmacy for relief from their cold and flu symptoms. However, their over-the-counter treatments may have a dark side. The Food and Drug Agency notes that anyone taking more than one drug containing acetaminophen may be at risk for liver damage. Worse, the symptoms for acetaminophen overdose can be so subtle - cold- and flu-like symptoms to boot! - that they can go unnoticed for days.

Acetaminophen can be found in 600 medications, ranging from cold and flu treatments to painkillers, on the shelves today and, used correctly, the drug can be safe and effective. However, the maximum suggested daily allowance is 4,000 milligrams, which can be exceeded if a person takes a combination of drugs in an effort to shake off their cold symptoms.  

The FDA advises consumers to avoid taking more than one over-the-counter treatment that contains acetaminophen at the same time or consuming a prescription drug and an over-the-counter drug that contain acetaminophen at the same time. The bureau also says to parents that, if a drug that contains acetaminophen does not have a label stating the proper dosage for children of a certain age or weight, they should consult with their child's pediatrician.

As of January of 2011, overdoses of prescription medications containing acetaminophen accounted for half the cases of liver damage associated with the drug. People who have a history of liver problems should contact their doctor before using the drug.

The FDA has a list of drugs on their website that contain acetaminophen.

Acetaminophen has also been linked to hearing loss in women.