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Stanford researchers recently explored the potential benefits of transcranial magnetic stimulation or TMS in increasing hypnotizability, particularly for those with conditions like fibromyalgia.

The research employed a robust double-blind randomized controlled trial involving 80 participants. Half of the subjects received the actual TMS treatment, while the other half received a weaker version that could not penetrate the skull, following the same procedural steps. Hypnotizability, measured on a 10-point scale where scores of 9 or 10 indicate high hypnotizability, was the primary focus.

Using the SHIFT technique

Utilizing the Stanford Hypnosis Integrated with Functional Connectivity Targeted Transcranial Stimulation or SHIFT technique, the researchers conducted scans, including standard and functional MRI, to observe brain activity linked to hypnotizability. This approach allowed them not only to understand the neural correlates but also to pinpoint the optimal location for applying the magnetic coil during TMS.

Post-treatment assessments revealed a significant increase in hypnotizability among participants who received neurostimulation. Their scores rose by one point on the 10-point scale. In contrast, the control group, which did not receive the neurostimulation, showed no change in hypnotizability.

Postdoctoral fellow at Stanford and lead author Dr. Afik Faerman expressed optimism regarding the study's proof-of-concept nature. He anticipates that this research will pave the way for more effective utilization of hypnosis-based therapies, especially for individuals grappling with chronic pain conditions.

A non-invasive approach

A notable aspect of this study is its non-invasive nature. Transcranial magnetic stimulation, coupled with fMRI scans during the treatment process, holds significant implications for the field. Dr. Jean-Philippe Langevin, a director at Pacific Neuroscience Institute, sees potential applications beyond hypnosis, particularly in common treatments for conditions like post-traumatic stress disorder.

Dr. David Spiegel, professor of medicine at Stanford University and a co-supervisor on the study, emphasizes that hypnosis, despite being the oldest Western conception of psychotherapy, has at times fallen out of favor. However, this research sheds new light on its efficacy, showcasing its potential in conjunction with non-invasive neuromodulation techniques.