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Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect various tissues in the body. Find out its psychological symptoms below.

Can Lupus Cause Psychosis?

While commonly known for physical symptoms like joint pain and fatigue, lupus can also manifest psychological symptoms, including psychosis. Understanding these psychological manifestations is crucial for effective management and treatment.

Psychosis, though rare, can occur in people with lupus. This phenomenon may result from immune system activity or as a side effect of certain lupus medications. Research indicates that between 1.9% to 29.8% of people with lupus may experience psychosis, with most cases occurring within three years of diagnosis.

Why Lupus Leads to Psychosis

Lupus triggers the production of antibodies that mistakenly attack healthy tissues, including those in the brain and central nervous system. This attack, known as neuropsychiatric systemic lupus erythematosus (NPSLE), can contribute to psychosis symptoms. Additionally, certain antibodies, such as anti-ribosomal P, have been associated with psychosis in lupus patients.

Symptoms of Lupus-Induced Psychosis

Psychosis in lupus can manifest in various ways, including hallucinations, delusions and confused thinking. These symptoms may differ from person to person but generally involve experiencing sensory perceptions or holding false beliefs. Prompt recognition and treatment are essential for managing lupus-induced psychosis effectively.

Treatment Options

Treatment for lupus-induced psychosis typically involves a combination of antipsychotic medications and drugs to suppress immune activity. Corticosteroids, commonly used to manage lupus flares, may exacerbate psychosis symptoms and need careful monitoring. In some cases, adjusting medication dosage or discontinuing steroids may be necessary to alleviate psychosis.

Other Psychological Symptoms of Lupus

Beyond psychosis, lupus can manifest various other psychological symptoms, including depression, mania, cognitive difficulties, anxiety disorders and symptoms resembling ADHD. These symptoms can significantly impact a person's quality of life and often require tailored treatment approaches.

Conclusion

While lupus primarily affects the body's immune system, its impact extends to psychological well-being. Understanding and addressing psychological symptoms like psychosis are vital components of comprehensive lupus management. With appropriate treatment and support, people with lupus-induced psychosis can lead fulfilling lives despite the challenges posed by the disease.