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Findings from biotech startup Lactocore's study showed that a short peptide called LCGM-10, extracted from cow's milk, might offer potential in treating depression owing to its robust stimulatory effects, akin to caffeine.

Peptides in milk are recognized for their ability to influence brain function by regulating neurotransmitter systems. The new study published in Frontiers in Behavioral Neuroscience details the scientific validity of the peptide's potential in depression treatment.

Spearheaded by Lactocore's team, the study delved into the potential therapeutic benefits of peptides found in milk, which can influence brain functions by modulating neurotransmitter systems. Utilizing structural bioinformatics and machine learning, the team identified regulatory peptides in milk and other natural sources, aiming to develop them into viable drug candidates for market release.

The team identified several new peptides that target the metabotropic glutamate receptor 5 (mGluR5), a key player in various brain-related disorders such as fragile X syndrome (FXS), depression, Parkinson's disease, Alzheimer's disease, attention deficit hyperactivity disorder (ADHD) and addiction.

Following chemical optimization, the peptides underwent rigorous testing in animal studies, with LCGM-10 emerging as a particularly promising candidate.Notably, LCGM-10 showcases potential efficacy in treating attention deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), and conditions associated with impulsive behavior, such as drug addiction and gambling, while minimizing the side effects often linked with current therapies.

The research covered a wide spectrum of conditions, including neurological diseases, anxiety disorders, diabetes and even avenues for healthy life extension.

"The results warrant further studies of LCGM-10 as a prospective alternative to current drugs available to patients," Dr. Malyshev, a key figure in the research, explained, Tech reported.

"This peptide can revolutionize medical care for people with attention deficit, obsessive-compulsive disorder, or addictions by offering a treatment that not only meets the high standards of efficacy demanded in today's market but does so while minimizing side effects."